Two-dimensional layered nanomaterials for tumor diagnosis and treatment

Abstract With the evolution of nanomedicine, past decades witnessed diversified nanomaterials as marvelous anti-tumor tools ushering in a new era tumor diagnosis and treatment. Among them, two-dimensional layered nanomaterial an emerging class has one dimension less than 100 nm, showing high specific area thinnest sheet-like structure (Liu S, Pan X, Liu H. Twodimensional for photothermal therapy. Angew Chem Int Ed 2020;59:5890–900). The discovery graphene drove exploration various treatment including graphene-based nanomaterials, black phosphorus (BP), transition metal dichalcogenides (TMDs), double hydroxides (LDHs), bismuth oxyhalides (BiOX, X=F, Cl, Br, I) (Ma H, Xue MQ. Recent advances applications nanomaterial: therapy beyond. J Mater 2021;9:17569). On hand, they exhibit strong near-infrared (NIR) absorption capacity optimizing corresponding properties by adjusting crystal structure. other own unique strengths such fantastic physicochemical (graphene-based nanomaterials), loading distinct phase-dependent optical chemical response to microenvironment large X-ray attenuation coefficient (BiOX). Herein, we briefly introduce three typical their prospects future research priorities are concluded.